牙本质基质蛋白1多克隆抗体/牙本质基质蛋白1多克隆抗体

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英文名 ：DMP1 Polyclonal Antibody

库存 ：现货

供应商 ：亚科因

CAS号 ：Null

规格 ：30μl///100μl///200μl

关键词：DMP1抗体;牙本质基质蛋白1抗体;牙本质基质蛋白1;Dentin matrix acidic phosphoprotein 1; DMP-1; Dentin matrix protein 1;ABP58392

中文名称：牙本质基质蛋白1多克隆抗体/DMP1 Polyclonal Antibody

英文名称：DMP1 Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP58392.pdf

产品描述：兔抗-牙本质基质蛋白1 多克隆抗体

Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. DMP1 structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for DMP1.

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