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免疫原 :Recombinant protein of human GAPDH
亚型 :IgG
形态 :液体
保存条件 :Store at -20°C. Avoid freeze / thaw cycles.
克隆性 :单克隆
适应物种 :Human Mouse Rat
保质期 :5年
抗原来源 :Recombinant protein of human GAPDH
目录编号 :K106389P
级别 :BR
库存 :99
供应商 :北京索莱宝科技有限公司
宿主 :Rabbit
应用范围 :WB
靶点 :GAPDH
抗体英文名 :Anti-GAPDH Polyclonal Antibody
抗体名 :GAPDH GAPD;CDABP0047;OK/SW-cl.12;G3PD;HEL-S-162eP
规格 :50ul/100ul
产品简介
单位 | 支 |
靶标 | GAPDH |
别名 | G3PD;GAPD;HEL-S-162eP |
宿主 | Rabbit |
稀释比例 | WB 1:8000-12000. IHC 1:50-200. |
Gene ID | 2597 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P04406 |
蛋白分子量 | 32/36kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Nucleus |
免疫原 | Recombinant protein of human GAPDH |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. |
Public Immunogen Range | 1-336aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human Rat Mouse |
应用 | WB IHC |
规格 | 50ul 100ul |
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示:
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Immunohistochemistry of paraffin-embedded Human breast cancer using GAPDH antibody diluted at 1:100
Western blot analysis with GAPDH antibody diluted at 1:8000;Lane:HEK293,HeLa,293T,HepG2,COS7,A431,Mouse liver,Mouse kidney,Rat liver
北京索莱宝科技有限公司
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入驻年限:12年