产品详情
文献和实验
相关推荐
英文名 :AZD1283
供应商 :上海恪敏生物科技有限公司
CAS号 :919351-41-0
规格 :1mg
AZD1283 is an effective P2Y12 receptor antagonist (EC50: 3.0 ug/kg/min, binding IC50: 11 nM). AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithrombotic ED50 values of 3.0 and 10 μg/kg/min, respectively. The doses induced the increase in bleeding time at 33 and 100 μg/kg/min for 3- and 13-fold, respectively. Thus, the therapeutic index (TI) was ≥10 for both compounds.上海恪敏生物科技有限公司
实名认证
金牌会员
入驻年限:12年