PKACa2/RIa2

保存条件 ：2-8度

保质期 ：1年

英文名 ：PKACa2/RIa2

库存 ：999

供应商 ：上海淳麦

规格 ：/5ug/20ug/1mg

产品英文名称：
Recombinant Protein Kinase A Inactive holoenzyme type 1 alpha

英文简称:
PKACa2/RIa2

中文名称:
重组蛋白激酶A失活全酶类型1α

背景资料:
The protein kinase A holoenzyme is a heterotetramer composed of two types of subunits: Catalytic and Regulatory. The Catalyticsubunit contains the enzyme’s active site. It also contains a domain that binds ATP and a domain that binds the regulatory subunit. The Regulatory subunit consists oftwo molecules which bind one another in an anti-parallel orientation to form a homodimer； for type I subunits- this binding is covalent via disulfide bonds. This subunit also has has two domains that bind cyclic AMP， a domain that interacts with a catalytic subunit， and an "auto-inhibitory" domain that serves as a substrate or pseudosubstrate for the catalytic subunit. Regulatory subunits may also have biologic activity distinct from their role in modulating catalytic subunit activity. Regulatory subunits exist in two major forms， RI and RII， with each form having two subtypes designated alpha and beta. Each of the four isotypes of the regulatory subunit is encoded by a di大肠杆菌中重组表达erent gene. In addition， thrInactive holoenzyme consisting of one dimeric regulatory subunit type I alpha and two monomeric catalytic subunits （cAMP-free）.Protein Kinase A Recombinant is purified by proprietary chromatographic techniques. isotypes of the catalytic subunit have bInactive holoenzyme consisting of one dimeric regulatory subunit type I alpha and two monomeric catalytic subunits （cAMP-free）.Protein Kinase A Recombinant is purified by proprietary chromatographic techniques.n identified （alpha， beta and gamma）. The di大肠杆菌中重组表达erent isotypes tend to have di大肠杆菌中重组表达erent distributions within cells and among tissues. Type I enzymes inhabit cytoplasmic， soluble fractions of the cell， whereas type II enzymes tend to associate with cellular membranes.

产品描述:
Inactive holoenzyme consisting of one dimeric regulatory subunit type I alpha and two monomeric catalytic subunits （cAMP-free）.Protein Kinase A Recombinant is purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

序列:


溶解建议:
提供的蛋白激酶A失活全酶类型1α（PKACa2/RIa2）产品为过滤灭菌的透明溶液；其中蛋白激酶A失活全酶类型1α（PKACa2/RIa2）产品溶解于50%甘油溶液中.

保存建议：
蛋白激酶A失活全酶类型1α（PKACa2/RIa2）溶液可以在4℃冷藏保存2-4周；如果想延长保存时间，建议分装后置于-20℃冻存.请避免反复冻融.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。
上海淳麦生物为ProSpec国内代理销售经销商，详细的产品信息请和我们联系：免费热线：4006815880 微信电话 13770640776