Anti-GHRL antibody

供应商 ：上海机纯实业有限公司

库存 ：大量

克隆性 ：单克隆

保质期 ：12个月

抗体英文名 ： Anti-GHRL antibody

宿主 ：Rabbit

适应物种 ：人/动物/植物

应用范围 ： ELISA, WB

浓度 ：0.5 mg/ml

保存条件 ：-20°C

规格 ：25 μl/100 μl/200 μl

Anti-GHRL antibody

Cat. No.    JC263014
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-GHRL rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human GHRL
Reactivity                 Human, Mouse, Rat
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 GHRL
Full name                 ghrelin/obestatin prepropeptide
Synonyms    MTLRP
Swissprot    Q9UBU3

Target Background
This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.

Anti-GHRL antibody
Applications
Immunohistochemistry
Predicted cell location: Secreted
Positive control: Human breast cancer
Recommended dilution: 25-100    Predicted cell location: Secreted
Positive control: Human colorectal cancer
Recommended dilution: 25-100