Anti-DMRT3 antibody

供应商 ：上海机纯实业有限公司

库存 ：大量

克隆性 ：多克隆

保质期 ：12个月

抗体英文名 ：Anti-DMRT3 antibody

宿主 ：Rabbit

适应物种 ：人/动物/植物

应用范围 ：ELISA, WB

浓度 ：0.5 mg/ml

保存条件 ：-20°C

规格 ：25 μl/100 μl/200 μl

Anti-DMRT3 antibody

Cat. No.     JC222241
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-DMRT3 rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Fusion protein of human DMRT3
Reactivity                 Human, Mouse, Rat
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 DMRT3
Full name                 doublesex and mab-3 related transcription factor 3
Synonyms    DMRTA3
Swissprot    Q9NQL9

Target Background
The DMRT (doublesex and mab-3 related transcription factor) genes encode a large family of transcription factors that are related to the Drosophila doublesex proteins. Expressed primarily in the gonads, DMRT proteins contain cysteine-rich DNA-binding motifs and are thought to play an important role in sexual development. DMRT3 (doublesex and mab-3 related transcription factor 3), also known as DMRTA3, is a 472 amino acid protein that contains one DM DNA-binding domain and belongs to the DMRT family. Localized to the nucleus, DMRT3 is expressed specifically in testis and is thought to regulate transcriptional events during early sexual development. The gene encoding DMRT3 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human ovarian cancer
Recommended dilution: 100-300    Predicted cell location: Cytoplasm
Positive control: Human breast cancer
Recommended dilution: 100-300