文献支持RT1662·Anti-WNT4 Antibody

靶点 ：WNT4

浓度 ：2 mg/mL.

应用范围 ：WB,IP,IF,IHC-P

宿主 ：Mouse

适应物种 ：Human, Mouse, Rat

保质期 ：1年

供应商 ：Huabio

标记物 ：Non-conjugated

保存条件 ：Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

形态 ：Liquid

亚型 ：IgG1

免疫原 ：peptide

规格 ：50μl/100μl

Products of the highly conserved Wnt gene family, including Wnt-1 through Wnt-10, play key roles in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. Wnt-1, which is essential for normal development of the embryonic nervous system, contributes to hyperplasia and tumorigenic progression when improperly expressed in mammary tissue. Wnt-3 is also involved in tumorigenesis, and Wnt-2 and Wnt-4 may be associated with abnormal proliferation in human breast tissue.Wnt-1, Wnt-3 and Wnt-10b have been implicated along with FGF-3 in the development of mouse mammary tumor virus-induced mouse mammary carcinomas.Wnt family members have been shown to interact with Sonic hedgehog (Shh) in vivo to induce myogenesis in somitic tissue.