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靶点 :nNOS
浓度 :1 mg/mL.
应用范围 :WB,ICC,IHC-P,FC
宿主 :Rabbit
适应物种 :Human, Mouse, Rat
保质期 :1年
供应商 :Huabio
标记物 :Non-conjugated
保存条件 :Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
形态 :Liquid
亚型 :IgG
免疫原 :Synthetic peptide within C-terminal human nNOS.
规格 :50μl/100μl
Nitric oxide (NO) has a broad range of biological activities and has been implicated in signaling pathways in phylogenetically diverse species. Nitric oxide synthases (NOSs), the enzymes responsible for synthesis of NO, contain an N-terminal oxygenase domain and a C-terminal reductase domain. NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM-dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells. The inducible form of NOS, NOS2 (also designated iNOS), is Ca2+-independent and is expressed in a broad range of cell types.杭州华安生物技术有限公司
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入驻年限:7年