文献支持ET1611-7·Anti-Kv1.1 potassium channel Antibody

靶点 ：Kv1.1 potassium channel

浓度 ：1 mg/mL.

应用范围 ：WB,IHC-P,IP

宿主 ：Rabbit

适应物种 ：Human, Rat

保质期 ：1年

供应商 ：Huabio

标记物 ：Non-conjugated

保存条件 ：Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

形态 ：Liquid

亚型 ：IgG

免疫原 ：Synthetic peptide within human KCNA1 aa 400-440.

规格 ：50μl/100μl

Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K⁺ channels, and they vary in their gating and permeation properties, subcellular distribution, and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming -subunits (KVα), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KVβ subunits that modify the gating properties of the coexpressed KVα subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1.1, KV1.2, KV1.4, KV1.5 and KV1.6) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.