Anti-PAPPA-AS1 antibody

供应商 ：上海晶抗生物工程有限公司

库存 ：大量

克隆性 ：多克隆

保质期 ：1年

抗体英文名 ：Anti-PAPPA-AS1 antibody

宿主 ：Rabbit

适应物种 ：Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Sheep

应用范围 ：科研试验

保存条件 ：-20°C

规格 ：25 μl/100 μl/200 μl

Anti-PAPPA-AS1 antibody


Cat. No.     JK163127 
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-PAPPA-AS1 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human PAPPA-AS1
Reactivity                 Human
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 PAPPA-AS1
Full name                 PAPPA antisense RNA 1
Synonyms    DIPAS; TAF4B; PAPPAS; TAF2C2; PAPPAAS; PAPPA-AS; TAFII105; NCRNA00156
Swissprot    Q5QFB9

Target Background
PAPP A was originally isolated from pregnancy serum as heterotetrameric protein complex with molecular weight approximately 500 kDa, consisting of two PAPP A subunits disulfide-linked with two subunits of the proform of eosinophil major basic protein (proMBP). In such a complex proMBP functions as an inhibitor of PAPP A proteinase activity. PAPP A is widely used as a marker of some pathologies during pregnancy. Reduced level of PAPP A in pregnancy blood in the first trimester is associated with fetal Down syndrome. PAPP A is considered as one of the best biochemical markers in early pregnancy used to screen for Down syndrome during the first trimester (Wald, N. J. et al).