Anti-APC antibody

供应商 ： 上海机纯实业有限公司

库存 ：大量

克隆性 ：多克隆

保质期 ：12个月

抗体英文名 ：Anti-APC antibody

宿主 ：Rabbit

适应物种 ：人/动物/植物

应用范围 ：ELISA, WB

浓度 ：0.6 mg/ml

保存条件 ：-20°C

规格 ：25 μl/100 μl/200 μl

Anti-APC antibody

Cat. No.    JC161290        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-APC rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human APC
Reactivity                 Human, Mouse, Rat
Content                     0.6 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-APC antibody
Target information
Symbol                 APC
Full name                 adenomatous polyposis coli
Synonyms    GS; DP2; DP3; BTPS2; DP2.5; PPP1R46
Swissprot    P25054

Target Background
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Anti-APC antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 25-100    Predicted cell location: Cytoplasm
Positive control: Human gastric cancer
Recommended dilution: 25-100