Product overview
Description Anti-APBA2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human APBA2
Reactivity Human
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol APBA2
Full name amyloid beta (A4) precursor protein-binding, family A, member 2
Synonyms X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091
Swissprot Q99767
Target Background
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.
Anti-APBA2 antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 100-300 Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 100-300