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靶点 :her2
克隆性 :多克隆
抗体英文名 :Ado-trastuzumab emtansine
抗体名 :曲妥珠单抗-美坦新偶联物
规格 :5mg
PurchaseDescription
Ado-trastuzumab emtansine is a HER2-targeted antibody-drug conjugate which contains the humanized anti-HER2 IgG1, trastuzumab, covalently linked to the microtubule inhibitory drug DM1 via the stable thioether linker MCC. Trastuzumab is produced by Chinese hamster ovary cells, and DM1-MCC are produced by chemical synthesis. Ado-trastuzumab emtansine contains an average of 3.5 DM1 molecules per antibody.
Ado-trastuzumab emtansine is supplied at a concentration of 20 mg/mL as a sterile, clear and colorless, preservative-free solution, which contains polysorbate 20 [0.02% (w/v)], sodium succinate (10 mM), and sucrose [6% (w/v)] with a pH of 5.0.
Properties
Name | Ado-trastuzumab emtansine |
CAS NO. | 1018448-65-1 |
Type | Whole antibody |
Source | humanized (from mouse) |
Target | HER2 |
Clone | Monoclone |
Formula | C6448H9948N1720O2012S44 |
Molecular Weight | 149 kDa |
Antibody Form | Purified immunoglobulin |
Physical Form | Solution |
Grade Standard | Medicine Grade |
Place of Origin | China (Mainland) |
Storage | -70±15℃ for long-term storage, 2-8℃ for short-term storage, away from light. |
20 kilogram per year, Minimum order quantity is 1 gram.
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Material Safety Data Sheet
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Certificate Of Analysis
Detail information about the product please refer the website below:
https://en.wikipedia.org/wiki/Trastuzumab_emtansine
上海赛迈生物科技有限公司
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入驻年限:8年