Anti-KIR2DL5A antibody

供应商 ：江西江蓝纯生物试剂有限公司

库存 ：大量

克隆性 ：多克隆

保质期 ：1年

抗体英文名 ：Anti-KIR2DL5A antibody

宿主 ：Rabbit

浓度 ：1.02 mg/ml

保存条件 ：-20°C

规格 ：25 μl/100 μl/200 μl

Anti-KIR2DL5A antibody

Cat. No.     JC264353
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-KIR2DL5A rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Synthetic peptide of human KIR2DL5A
Reactivity                 Human
Content                     1.02 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 KIR2DL5A
Full name                 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A
Synonyms    CD158F; KIR2DL5; KIR2DL5.1; KIR2DL5.3
Swissprot    Q8N109

Target Background
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Applications
Western blotting
Predicted band size:41 kDa
Positive control:Human plasma solution 
Recommended dilution: 1000-5000