FITC标记的转录因子Tbx3抗体

FITC标记的转录因子Tbx3抗体

价格: ¥2980

品牌:LMAI Bio

货号:LM-10266R-FITC

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供应商 :上海联迈生物工程有限公司

库存 :大量

靶点 :详见说明书

级别 :1

目录编号 :LM-10266R-FITC

克隆性 :多克隆

抗原来源 :Rabbit

保质期 :1年

抗体英文名 :Anti-TBX3/FITC

抗体名 :Anti-TBX3/FITC

标记物 :FITC标记

宿主 :Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,

适应物种 :Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,

免疫原 :详见说明书

亚型 :IGg

形态 :粉末、液体、冻干粉

应用范围 :ICC=1:50-200 IF=1:50-200

浓度 :1mg/ml

保存条件 :-20 °C

规格 :100ul

FITC标记的转录因子Tbx3抗体
英文名称 Anti-TBX3/FITC
中文名称 FITC标记的转录因子Tbx3抗体
别    名 T-box protein 3; T-box transcription factor TBX3; TBX3; TBX3-ISO; TBX3 ISO; UMS; XHL; Bladder cancer related protein XHL; T box 3; TBX3_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 82kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TBX3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Tbx3 gene is a member of a phylogenetically conserved family of genes that share a common DNA binding domain, the T box. T box genes encode transcription factors involved in the regulation of developmental processes. Tbx3 is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.

Function:
Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.

Subcellular Location:
Nucleus (Potential).

Tissue Specificity:
Widely expressed.

DISEASE:
Defects in TBX3 are the cause of ulnar-mammary syndrome (UMS) [MIM:181450]. UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands.

Similarity:
Contains 1 T-box DNA-binding domain.

Database links:

Entrez Gene: 6926 Human

Entrez Gene: 21386 Mouse

Entrez Gene: 353305 Rat

Omim: 601621 Human

SwissProt: O15119 Human

SwissProt: P70324 Mouse

SwissProt: Q7TST9 Rat

Unigene: 129895 Human

Unigene: 219139 Mouse

Unigene: 162144 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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