Anti-GFI1B antibody

供应商 ：江西江蓝纯生物试剂有限公司

库存 ：大量

克隆性 ：多克隆

保质期 ：1年

抗体英文名 ：Anti-GFI1B antibody

宿主 ：Rabbit

浓度 ：0.72 mg/ml

保存条件 ：-20°C

规格 ：25 μl/100 μl/200 μl

Anti-GFI1B antibody

Cat. No.     JC263985
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-GFI1B rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human GFI1B
Reactivity                 Human
Content                     0.72 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 GFI1B
Full name                 growth factor independent 1B transcriptional repressor
Synonyms    BDPLT17; ZNF163B
Swissprot    Q5VTD9

Target Background
This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants.

Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 40-200    
            
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ml263985(GFI1B Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)    

ELISA
Recommended dilution: 5000-10000