FITC标记的HEG同源蛋白1抗体

供应商 ：上海联迈生物工程有限公司

库存 ：大量

靶点 ：详见说明书

级别 ：1

目录编号 ：LM-15449R-FITC

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：1年

抗体英文名 ：Anti-HEG1/FITC

抗体名 ：Anti-HEG1/FITC

标记物 ：FITC标记

宿主 ：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,

适应物种 ：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,

免疫原 ：详见说明书

亚型 ：IGg

形态 ：粉末、液体、冻干粉

应用范围 ：ICC=1:50-200 IF=1:50-200

浓度 ：1mg/ml

保存条件 ：-20 °C

规格 ：100ul

FITC标记的HEG同源蛋白1抗体

英文名称	Anti-HEG1/FITC
中文名称	FITC标记的HEG同源蛋白1抗体
别    名	HEG; HEG1; HEG1_HUMAN; KIAA1237; MST112; MSTP112; HEG homolog 1; Protein HEG homolog 1.
规格价格	100ul/2980元 购买        大包装/询价
说 明 书	100ul
研究领域	心血管  细胞生物  免疫学  信号转导
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
产品应用	ICC=1:50-200 IF=1:50-200   not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	144kDa
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human HEG1
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍	background: HEG1 (HEG homolog 1) is also known as HEG and is a 1,381 amino acid protein that exists as two alternatively spliced isoforms, one of which is a single-pass membrane protein and the other of which is secreted. HEG1, which is expressed in endothelial cells and smooth muscle cells of heart tissue, contains two EGF-like domains that play a role in calcium-binding events which may regulate concentric heart growth. The gene encoding HEG1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.  Function: Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity May act through the stabilization of endothelial cell junctions. Subunit: Interacts with CCM2 and KRIT1; KRIT1 markedly facilitates interaction with CCM2.  Subcellular Location: Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential). Cell junction. Isoform 2: Secreted (Potential). Similarity: Contains 2 EGF-like domains. Database links: Entrez Gene: 57493 Human Omim: 614182 Human SwissProt: Q9ULI3 Human Unigene: 477420 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.