FITC标记的单纯疱疹病毒1型转录调节因子ICP22抗体

供应商 ：上海联迈生物工程有限公司

库存 ：大量

靶点 ：详见说明书

级别 ：1

目录编号 ：LM-15398R-FITC

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：1年

抗体英文名 ：Anti-HHV11 ICP22/FITC

抗体名 ：Anti-HHV11 ICP22/FITC

标记物 ：FITC标记

宿主 ：Herpes Simplex Virus

适应物种 ：Herpes Simplex Virus

免疫原 ：详见说明书

亚型 ：IGg

形态 ：粉末、液体、冻干粉

应用范围 ：ICC=1:50-200 IF=1:50-200

浓度 ：1mg/ml

保存条件 ：-20 °C

规格 ：100ul

FITC标记的单纯疱疹病毒1型转录调节因子ICP22抗体

英文名称	Anti-HHV11 ICP22/FITC
中文名称	FITC标记的单纯疱疹病毒1型转录调节因子ICP22抗体
别    名	US1; Herpes simplex virus 1; Herpes Simplex Virus; Herpes Simplex Virus Type 1; HSV 1; Human herpesvirus 1; Human herpesvirus type 1; ICP22_HHV11; Transcriptional regulator ICP22; Immediate-early protein IE68; Infected cell protein 22; ICP22.
规格价格	100ul/2980元 购买        大包装/询价
说 明 书	100ul
研究领域	细胞生物  免疫学  微生物学  细菌及病毒
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Herpes Simplex Virus
产品应用	ICC=1:50-200 IF=1:50-200   not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	46kDa
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human HSV1
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍	background: Herpes simplex type 1 (HSV-1) belongs to a family that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoproteins spikes. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell.  Function: Functions as a general transcriptional regulator of cellular and viral mRNAs mainly by mediating changes on the host RNA polymerase II. One change, which is UL13 independent, is the rapid loss of Pol II forms bearing Ser-2 phosphorylation. A second change, which is UL13 dependent, is the appearance of an intermediate form of Pol II that differs from the normal hypo- and hyperphosphorylated forms. These Pol II modifications immediately inhibit host genome transcription, leading to cell cycle deregulation and loss of efficient antiviral response.  Subcellular Location: Host nucleus. Note=Localizes in small nuclear bodies early in infection then moves to a more diffuse distribution in viral compartments as infecion progresses. Post-translational modifications: Tyrosine phosphorylated. Similarity: Belongs to the herpesviridae IE68 family.  Database links: Entrez Gene: 2703435 HHV11SwissProt: P04485 HHV11 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.