FITC标记的RNA结合蛋白NOB1抗体

供应商 ：上海联迈生物工程有限公司

库存 ：大量

靶点 ：详见说明书

级别 ：1

目录编号 ：LM-8857R-FITC

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：1年

抗体英文名 ：Anti-NOB1/FITC

抗体名 ：Anti-NOB1/FITC

标记物 ：FITC标记

宿主 ：Human, Mouse, Rat, Dog, Pig, Cow, Horse,

适应物种 ：Human, Mouse, Rat, Dog, Pig, Cow, Horse,

免疫原 ：详见说明书

亚型 ：IGg

形态 ：粉末、液体、冻干粉

应用范围 ：ICC=1:50-200 IF=1:50-200

浓度 ：1mg/ml

保存条件 ：-20 °C

规格 ：100ul

FITC标记的RNA结合蛋白NOB1抗体

英文名称	Anti-NOB1/FITC
中文名称	FITC标记的RNA结合蛋白NOB1抗体
别    名	Adenocarcinoma antigen recognized by T lymphocytes 4; ART4; MST158; MSTP158; Nin one binding protein; NIN1/RPN12 binding protein 1 homolog (S. cerevisiae); nob1; NOB1_HUMAN; NOB1P; Phosphorylation regulatory protein HP-10; Protein ART-4; Protein ART4; PSMD8 binding protein 1; PSMD8BP1; RNA binding protein NOB1; RNA-binding protein NOB1.
规格价格	100ul/2980元 购买        大包装/询价
说 明 书	100ul
研究领域	肿瘤  细胞生物  染色质和核信号  结合蛋白  表观遗传学
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Dog, Pig, Cow, Horse,
产品应用	ICC=1:50-200 IF=1:50-200   not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	47kDa
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human NOB1
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍	background: NOB1P is a 412 amino acid nuclear protein that is involved in proteosome biogenesis and is required for the final step in 18S rRNA maturation. NOB1P contains a PIN domain, which functions as a nuclease in nonsense-mediated mRNA decay and is required for pre-rRNA cleavage. NOB1P interacts with Rent2, which is involved in nonsense-mediated decay of mRNAs containing premature stop codons. Expressed in placenta, spleen, endothelial cells, liver and lung, NOB1P is essential for the synthesis of 40S ribosome subunits. Supression of the gene encoding NOB1P inhibits the processing of the 20S pre-rRNA to the mature 18S rRNA, therefore leading to accumulation of high levels of 20S pre-rRNA with degradation intermediates. Function: May play a role in mRNA degradation. Subcellular Location: Nucleus. Tissue Specificity: Detected in liver, lung, placenta, endothelial cells and spleen. Similarity: Belongs to the NOB1 family. Contains 1 PINc domain. Database links: Entrez Gene: 28987 Human Entrez Gene: 67619 Mouse Entrez Gene: 291996 Rat Omim: 613586 Human SwissProt: Q9ULX3 Human SwissProt: Q8BW10 Mouse SwissProt: Q6VEU1 Rat Unigene: 271695 Human Unigene: 334793 Mouse Unigene: 102586 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.