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英文名 :≥98%(HPLC)
库存 :50
CAS号 :912445-05-7
规格 :5mg/25mg/100mg
一种有效的PARP1和PARP2抑制剂,Ki分别为5.2nM和2.9nM。ABT888 has been shown to inhibit PARP-1 and PARP-2, enzymes which catalyze the addition of ADP-ribose units to proteins that mediate DNA repair pathways. PARP is also important in initiating apoptosis, and thus inhibition of these enzymes reduces the rate of apoptosis in DNA-damaged cells。北京普西唐生物科技有限公司
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