Noscapine HCl（Nectodon）

英文名 ：≥98%（HPLC）

库存 ：50

CAS号 ：912-60-7

规格 ：1g/5g

一种缓激肽受体拮抗剂，抑制卡巴胆碱诱导的磷酸肌醇周转，促进佛司可林诱导的中枢神经系统cAMP增加。Noscapine hydrochloride is the hydrochloride form of Noscapine. Noscapine is an opioid alkaloid with several actions. Antagonist at Bradykinin B Receptor (bradykinin receptors) (pA2 = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated cAMP increases in CNS tissues. Additionally Noscapine binds to tubulin, arrests cells in mitosis and induces apoptosis. Blocks proliferation of human leukemia and multiple myeloma cells. Furthermore, Noscapine modulates IKK activation, suppressing the NF-κB signaling pathway. Exhibits anti-inflammatory activity. Noscapine hydrochloride is an inhibitor of Tubulin。