Anti-HIST1H2AB antibody

供应商 ：江西江蓝纯生物试剂有限公司

库存 ：大量

克隆性 ：多克隆

保质期 ：1年

抗体英文名 ：Anti-HIST1H2AB antibody

宿主 ：Rabbit

浓度 ：0.2 mg/ml

保存条件 ：-20°C

规格 ：25 μl/100 μl/200 μl

Anti-HIST1H2AB antibody

Cat. No.     JC261744
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-HIST1H2AB rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human HIST1H2AB
Reactivity                 Human, Mouse
Content                     0.2 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 HIST1H2AB
Full name                 histone cluster 1, H2ab
Synonyms    H2A/m; H2AFM
Swissprot    P04908

Target Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human cervical cancer
Recommended dilution: 50-200    Predicted cell location: Nucleus
Positive control: Human colon cancer
Recommended dilution: 50-200
            
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using ml261744(HIST1H2AB Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)    The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using ml261744(HIST1H2AB Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:14 kDa
Positive control:Hela, 231 and K562 cells,human fetal brain tissue 
Recommended dilution: 200-1000