FITC标记的串珠状纤维结构蛋白1抗体

FITC标记的串珠状纤维结构蛋白1抗体

价格: ¥2980

品牌:LMAI Bio

货号:LM-13172R-FITC

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供应商 :上海联迈生物工程有限公司

库存 :大量

靶点 :详见说明书

级别 :1

目录编号 :LM-13172R-FITC

克隆性 :多克隆

抗原来源 :Rabbit

保质期 :1年

抗体英文名 :Anti-Filensin/FITC

抗体名 :Anti-Filensin/FITC

标记物 :FITC标记

宿主 :Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,

适应物种 :Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,

免疫原 :详见说明书

亚型 :IGg

形态 :粉末、液体、冻干粉

应用范围 :ICC=1:50-200 IF=1:50-200

浓度 :1mg/ml

保存条件 :-20 °C

规格 :100ul

FITC标记的串珠状纤维结构蛋白1抗体
英文名称 Anti-Filensin/FITC
中文名称 FITC标记的串珠状纤维结构蛋白1抗体
别    名 Beaded filament structural protein 1; Beaded filament structural protein 1 filensin; BFSP1; BFSP1_HUMAN; CP115; CP94; CP95; Cytoskeletal protein, 115 KD; Filensin; Lens fiber cell beaded filament structural protein CP 115; Lens fiber cell beaded-filament structural protein CP 115; Lens intermediate filament like heavy; Lens intermediate filament-like heavy; LIFL H; LIFL-H.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Filensin
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Filensin, also referred to as CP94, CP95, or CP97, is an eye lens fiber, membrane-associated, cytoskeletal intermediate filament (IF) protein that is required for the assembly of beaded filaments, cytoskeletal networks that are necessary for the long-term maintenance of optical clarity. Phakinin copolymerizes with Filensin to make up the filamentous structures present in the beaded filaments. Filensin is also crucial for lens development since it regulates lens fiber cell shape conformation and lens transparency. Filensin contains a C-terminal non-α-helical domain that contributes in several ways to its function. The head domain of Filensin includes a di-arginine/aromatic amino acid motif that contains a potential protein kinase A phosphorylation site. 

Subunit:
Associates with BFSP2. 

Subcellular Location:
Membrane. Cytoplasm. Cytoplasm > cytoskeleton. Membrane- and cytoskeleton-associated.

Tissue Specificity:
Lens.

DISEASE:
Defects in BFSP1 are the cause of cataract cortical juvenile-onset (CCJO) [MIM:611391]. A juvenile-onset cataract with opacities restricted to the cortex of the lens, not involving the nucleus.

Similarity:
Belongs to the intermediate filament family.

Database links:
UniProtKB/Swiss-Prot: Q12934.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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