Anti-KMT2B antibody

Anti-KMT2B antibody

价格: 询价

品牌:gelatins

货号:JLC162841

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克隆性 :多克隆

抗体名 :Anti-KMT2B antibody

适应物种 :人/动物/植物

浓度 :1.2 mg/ml

保存条件 :-20°C

规格 :25 μl/100 μl/200 μl

Anti-KMT2B antibody

Cat. No.     JLC162841
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-KMT2B rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human KMT2B
Reactivity                 Human, Mouse
Content                     1.2 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification



Target information
Symbol                 KMT2B
Full name                 lysine (K)-specific methyltransferase 2B
Synonyms    HRX2; MLL2; MLL4; TRX2; WBP7; MLL1B; WBP-7; CXXC10
Swissprot    Q9UMN6

Target Background
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.

 

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