FITC标记的早期发育调控蛋白1/EDR1抗体

供应商 ：上海联迈生物工程有限公司

库存 ：大量

靶点 ：详见说明书

级别 ：1

目录编号 ：LM-12302R-FITC

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：1年

抗体英文名 ：Anti-PHC1/FITC

抗体名 ：Anti-PHC1/FITC

标记物 ：FITC标记

宿主 ：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,

适应物种 ：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,

免疫原 ：详见说明书

亚型 ：IGg

形态 ：粉末、液体、冻干粉

应用范围 ：ICC=1:50-200 IF=1:50-200

浓度 ：1mg/ml

保存条件 ：-20 °C

规格 ：100ul

FITC标记的早期发育调控蛋白1/EDR1抗体

英文名称	Anti-PHC1/FITC
中文名称	FITC标记的早期发育调控蛋白1/EDR1抗体
别    名	Early development regulatory protein 1; EDR1 PH1; hPH1; mPH1; PH1; EDR1; Polyhomeotic-like protein 1; Rae28; PHC1_HUMAN.
规格价格	100ul/2980元 购买        大包装/询价
说 明 书	100ul
研究领域	细胞生物  发育生物学  干细胞  转录调节因子  表观遗传学
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
产品应用	ICC=1:50-200 IF=1:50-200   not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	105kDa
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from Human EDR1/PHC1
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍	background: PHC1 is a 1,004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain. PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Function: PHC1 is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The Polycomb group (PcG) genes are essential for maintenance of appropriate expression patterns of developmental master regulators, such as Hox genes, and thus are essential for proper development. PHC1 is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. PHC1, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein. Subcellular Location: Nuclear. Similarity: Contains 1 FCS-type zinc finger.  Contains 1 SAM (sterile alpha motif) domain.  Database links: Entrez Gene: 1911 Human Omim: 602978 Human SwissProt: P78364 Human Unigene: 305985 Human   Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.