Anti-TM7SF2 antibody

供应商 ：上海晶抗生物工程有限公司

库存 ：大量

克隆性 ：多克隆

保质期 ：1年

抗体英文名 ：Anti-TM7SF2 antibody

宿主 ：Rabbit

适应物种 ：Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Sheep

应用范围 ：科研试验

保存条件 ：-20°C

规格 ：25 μl/100 μl/200 μl

Anti-TM7SF2 antibody

Cat. No.    JK262376     
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-TM7SF2 rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human TM7SF2
Reactivity                 Human, Mouse
Content                     0.6 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 TM7SF2
Full name                 transmembrane 7 superfamily member 2
Synonyms    ANG1; NET47; DHCR14A
Swissprot    O76062

Target Background
Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol to 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol and NADP+.