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供应商 :上海晶抗生物工程有限公司
库存 :大量
克隆性 :多克隆
保质期 :1年
抗体英文名 :Anti-GHRL antibody
宿主 :Rabbit
适应物种 :Human,Mouse,Rat,Chicken,Dog,Cow,Rabbit,Sheep
应用范围 :科研试验
保存条件 :-20°C
规格 :25 μl/100 μl/200 μl
Anti-GHRL antibody
Cat. No. JK261708
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-GHRL rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human GHRL
Reactivity Human, Mouse, Rat
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol GHRL
Full name ghrelin/obestatin prepropeptide
Synonyms MTLRP
Swissprot Q9UBU3
Target Background
This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.
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入驻年限:9年