FITC标记的EB病毒核抗原-3A抗体

FITC标记的EB病毒核抗原-3A抗体

价格: ¥2980

品牌:LMAI Bio

货号:LM-0820R-FITC

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供应商 :上海联迈生物工程有限公司

库存 :大量

靶点 :详见说明书

级别 :1

目录编号 :LM-0820R-FITC

克隆性 :多克隆

抗原来源 :Rabbit

保质期 :1年

抗体英文名 :Anti-EBNA 3A/FITC

抗体名 :Anti-EBNA 3A/FITC

标记物 :FITC标记

宿主 :EBV/HHV4

适应物种 :EBV/HHV4

免疫原 :详见说明书

亚型 :IGg

形态 :粉末、液体、冻干粉

应用范围 :IF=1:50-200

浓度 :1mg/ml

保存条件 :-20 °C

规格 :100ul

FITC标记的EB病毒核抗原-3A抗体
英文名称 Anti-EBNA 3A/FITC
中文名称 FITC标记的EB病毒核抗原-3A抗体
别    名 nuclear antigen EBNA-3; Epstein-Barr nuclear antigen 3; EBV nuclear antigen 3; EBNA-3; Epstein-Barr nuclear antigen 3A; EBV nuclear antigen 3A; EBNA-3A; Epstein Barr Virus; EBV-NA3; EBNA3_EBVG.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 EBV/HHV4
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 103kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human herpesvirus 4 EBNA 3A (321-345aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
EBNA3A is a latent viral nuclear protein expressed in Epstein Barr Virus (EBV) transformed lymphoblastic cell lines. It is also found in some immunoblastic lymphomas in vivo. This viral nuclear protein is essential for EBV mediated transformation of B lymphocytes. The EBNA3A functions as a transcriptional regulator though the target genes are currently unknown. 

Function:
Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop.

Subunit:
Interacts with human UCKL1. Interacts with host CTPB1; this interaction seems important for EBNA3-mediated transcriptional repression. Interacts with host RBPJ.

Subcellular Location:
Host nucleus matrix. Note=Associated with the nuclear matrix.

Similarity:
Belongs to the herpesviridae EBNA-3 family.

Database links:
Entrez Gene: 3783762 EBVG 
SwissProt: Q3KST2 EBVG


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

EB病毒核抗原-3(nuclear antigen EBNA-3)是EB病毒编码核蛋白,位于细胞核的新的酶聚合体,主要作为转录调节因子,指导蛋白与蛋白之间相互作用,为核糖核苷酸补救途径的一部分.

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