Anti-NEB antibody

克隆性 ：多克隆

抗体名 ：Anti-NEB antibody

适应物种 ：人/动物/植物

浓度 ：0.6 mg/ml

保存条件 ：-20°C

规格 ：25 μl/100 μl/200 μl

Anti-NEB antibody

Cat. No.     JLC161020
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-NEB rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human NEB
Reactivity                 Human
Content                     0.6 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 NEB
Full name                 nebulin
Synonyms    NEM2, NEB177D
Swissprot    P20929

Target Background
This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein. The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules. Protein isoform sizes vary from 600 to 800 kD due to alternative splicing that is tissue-, species-,and developmental stage-specific. Of the 183 exons in the nebulin gene, at least 43 are alternatively spliced, although exons 143 and 144 are not found in the same transcript. Of the several thousand transcript variants predicted for nebulin, the RefSeq Project has decided to create three representative RefSeq records. Mutations in this gene are associated with recessive nemaline myopathy.