Anti-GJB2 antibody

克隆性 ：多克隆

抗体名 ：Anti-GJB2 antibody

适应物种 ：人/动物/植物

浓度 ：2.3 mg/ml

保存条件 ：-20°C

规格 ：25 μl/100 μl/200 μl

Anti-GJB2 antibody

Cat. No.     JLC160410
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-GJB2 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human GJB2
Reactivity                 Human, Rat
Content                     2.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 GJB2
Full name                 gap junction protein, beta 2, 26kDa
Synonyms    HID, KID, PPK, CX26, DFNA3, DFNB1, NSRD1, DFNA3A, DFNB1A
Swissprot    P29033

Target Background
This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.