Product overview Description Anti-CLDN10 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Synthetic peptide of human CLDN10 Reactivity Human Content 0.6 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol CLDN10 Full name claudin 10 Synonyms OSP-L, CPETRL3 Swissprot P78369
Target Background This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml260408(CLDN10 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)