Anti-CATSPER3 antibody

供应商 ：江西江蓝纯生物试剂有限公司

库存 ：大量

克隆性 ：多克隆

保质期 ：1年

抗体英文名 ：Anti-CATSPER3 antibody

宿主 ：Rabbit

浓度 ：0.4 mg/ml

保存条件 ：-20°C

规格 ：25 μl/100 μl/200 μl

Anti-CATSPER3 antibody

Cat. No.     JLC222040        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CATSPER3 rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Fusion protein of human CATSPER3
Reactivity                 Human, Mouse
Content                     0.4 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 CATSPER3
Full name                 cation channel, sperm associated 3
Synonyms    CACRC
Swissprot    Q86XQ3

Target Background
CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. Mutations in any of the genes encoding CatSper family proteins can result in male infertility. CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization.

Applications
Western blotting
Predicted band size:46 kDa
Positive control:Mouse testis tissue 
Recommended dilution: 500-2000

Gel: 8%SDS-PAGE
Lysate: 40 μg
Lane: Mouse testis tissue
Primary antibody: ml222040(CATSPER3 Antibody) at dilution 1/350
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 2 minutes
                        
ELISA
Recommended dilution:2000-5000