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供应商 :上海联迈生物工程有限公司
库存 :大量
靶点 :详见说明书
级别 :1
目录编号 :LM-1862R-FITC
克隆性 :多克隆
抗原来源 :Rabbit
保质期 :1年
抗体英文名 :Anti-MMP17/FITC
抗体名 :Anti-MMP17/FITC
标记物 :FITC标记
宿主 :Human, Mouse, Rat,
适应物种 :Human, Mouse, Rat,
免疫原 :详见说明书
亚型 :IGg
形态 :粉末、液体、冻干粉
应用范围 :IF=1:50-200
浓度 :1mg/ml
保存条件 :-20 °C
规格 :100ul
FITC标记的基质金属蛋白酶-17抗体英文名称 | Anti-MMP17/FITC |
中文名称 | FITC标记的基质金属蛋白酶-17抗体 |
别 名 | Matrix metalloproteinase-17; MMP-17; MMP 17; MMP17; MTMMP 4; Matrix metalloproteinase 17; Matrix metalloproteinase 17 membrane inserted; Membrane type 4 matrix metalloproteinase; Membrane type matrix metalloproteinase 4; MT MMP 4; MT MMP4; MT4 MMP; MT4MMP. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 免疫学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 48/63kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MMP17 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage. [provided by RefSeq, Jul 2008] Function: Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin. Subcellular Location: Isoform Long: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix. Tissue Specificity: Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-transformed cell types. Post-translational modifications: The precursor is cleaved by a furin endopeptidase. Similarity: Belongs to the peptidase M10A family. Contains 4 hemopexin-like domains. Database links: Entrez Gene: 4326 Human Entrez Gene: 23948 Mouse Entrez Gene: 288626 Rat Omim: 602285 Human SwissProt: Q9ULZ9 Human SwissProt: Q9R0S3 Mouse Unigene: 709245 Human Unigene: 42047 Mouse Unigene: 7971 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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