FITC标记的整合素αVβ1抗体

FITC标记的整合素αVβ1抗体

价格: ¥2980

品牌:LMAI Bio

货号:LM-2016R-FITC

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供应商 :上海联迈生物工程有限公司

库存 :大量

靶点 :详见说明书

级别 :1

目录编号 :LM-2016R-FITC

克隆性 :多克隆

抗原来源 :Rabbit

保质期 :1年

抗体英文名 :Anti-Integrin Alpha V + Beta 1/FITC

抗体名 :Anti-Integrin Alpha V + Beta 1/FITC

标记物 :FITC标记

宿主 :Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,

适应物种 :Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,

免疫原 :详见说明书

亚型 :IGg

形态 :粉末、液体、冻干粉

应用范围 :Flow-Cyt=1:50-200 IF=1:50-200

浓度 :1mg/ml

保存条件 :-20 °C

规格 :100ul

FITC标记的整合素αVβ1抗体
英文名称 Anti-Integrin Alpha V + Beta 1/FITC
中文名称 FITC标记的整合素αVβ1抗体
别    名 fibronectin receptor alpha; ITGAV; CD51; DKFZp686A08142; MSK8; Msk 8; VNR; similar to Integrin alpha-V precursor; Vitronectin receptor subunit alpha; CD51 antigen; HGNC; Vitronectin receptor alpha polypeptide; Vitronectin receptor alpha polypeptide antigen CD51; VNRA.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  细胞膜受体  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
产品应用 Flow-Cyt=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 114kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic Mixed peptides 915-948/1048(human Integrin αV)+ 21-70/798(human Integrin β1)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells.
Integrin alpha 5 belongs to the integrin alpha chain family. It contains seven FG-GAP repeats.
Integrin beta 1 belongs to the integrin beta chain family. It contains one VWFA domain.
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein se
ems to enhance angiogenesis in Kaposi's sarcoma lesions.

Function:
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Subcellular Location:
Membrane.

Similarity:
Belongs to the integrin alpha chain family. 
Contains 7 FG-GAP repeats.

Database links:

Entrez Gene: 3685 Human

Omim: 193210 Human

SwissProt: P06756 Human

Unigene: 436873 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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