FITC标记的Toll样受体11抗体

供应商 ：上海联迈生物工程有限公司

库存 ：大量

靶点 ：详见说明书

级别 ：1

目录编号 ：LM-2694R-FITC

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：1年

抗体英文名 ：Anti-TLR11/FITC

抗体名 ：Anti-TLR11/FITC

标记物 ：FITC标记

宿主 ：Mouse, Rat, Horse, Rabbit,

适应物种 ：Mouse, Rat, Horse, Rabbit,

免疫原 ：详见说明书

亚型 ：IGg

形态 ：粉末、液体、冻干粉

应用范围 ：ICC=1:50-200 IF=1:50-200

浓度 ：1mg/ml

保存条件 ：-20 °C

规格 ：100ul

FITC标记的Toll样受体11抗体

英文名称	Anti-TLR11/FITC
中文名称	FITC标记的Toll样受体11抗体
别    名	Toll like receptor 11; Gm287; MGC129352; MGC129353; RGD1564460; TLR11_MOUSE.
规格价格	100ul/2980元 购买        大包装/询价
说 明 书	100ul
研究领域	免疫学  细胞膜受体
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Mouse, Rat, Horse, Rabbit,
产品应用	ICC=1:50-200 IF=1:50-200   not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	99kDa
细胞定位	细胞膜
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from mouse TLR11
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍	background: Toll like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system. Function: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Subunit: Binds MYD88 via their respective TIR domains. Interacts with HSP90B1; this interaction is required for proper folding in the endoplasmic reticulum. Subcellular Location: Membrane; Single-pass type I membrane protein. Similarity: Belongs to the Toll-like receptor family. Contains 10 LRR (leucine-rich) repeats.  Contains 1 TIR domain. Database links: Entrez Gene: 239081 Mouse SwissProt: Q6R5P0 Mouse Unigene: 291512 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.