FITC标记的胆固醇酯转移蛋白抗体

供应商 ：上海联迈生物工程有限公司

库存 ：大量

靶点 ：详见说明书

级别 ：1

目录编号 ：LM-3694R-FITC

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：1年

抗体英文名 ：Anti-CETP/FITC

抗体名 ：Anti-CETP/FITC

标记物 ：FITC标记

宿主 ：Human

适应物种 ：Human

免疫原 ：详见说明书

亚型 ：IGg

形态 ：粉末、液体、冻干粉

应用范围 ：IF=1:50-200

浓度 ：1mg/ml

保存条件 ：-20 °C

规格 ：100ul

FITC标记的胆固醇酯转移蛋白抗体

英文名称	Anti-CETP/FITC
中文名称	FITC标记的胆固醇酯转移蛋白抗体
别    名	BPIFF; CETP; CETP_HUMAN; Cholesteryl ester transfer; Cholesteryl ester transfer protein; Cholesteryl ester transfer protein plasma; Cholesteryl ester transfer protein precursor; HDLCQ10; Lipid transfer protein I.
规格价格	100ul/2980元 购买        大包装/询价
说 明 书	100ul
研究领域	肿瘤  心血管  细胞生物  免疫学  信号转导  脂蛋白  新陈代谢
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human,
产品应用	IF=1:50-200   not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	53kDa
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human CETP
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍	background: High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease. Function: Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol.  Subcellular Location: Secreted, extracellular space. Tissue Specificity: Expressed by the liver and secreted in plasma. DISEASE: Defects in CETP are the cause of hyperalphalipoproteinemia type 1 (HALP1) [MIM:143470]. Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL). Similarity: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. Database links: Entrez Gene: 1071 Human Omim: 118470 Human SwissProt: P11597 Human SwissProt: P22687 Rabbit Unigene: 89538 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.  CETP系一疏水糖蛋白，胆固醇酯转运蛋白--介导HDL中的胆固醇与VLDL中的甘油三酯等交换，促进HDL中的胆固醇净转运，可促进胆固醇酯在细胞与血浆脂蛋白间的转运，参与胆固醇的逆转运过程