还原型 β-烟酰胺腺嘌呤二核苷酸 二钠盐 水合物

库存 ：大量

英文名 ：β-Nicotinamide adenine dinucleotide, reduced disodium salt hydrate

CAS号 ：606-68-8

保质期 ： 2年

供应商 ：上海瓦兰生物

保存条件 ：-20°

规格 ：50MG

性质

Related Categories	Bulk vials, Cofactors, Cofactors and Substrates,Core Bioreagents, NAD(P)(H) and Analogs, 更多...
InChI Key	FWBNCIFELNNJCX-UHOVGGJYSA-L
Quality Level	PREMIUM
assay	≥97% (HPLC)
	≥97% (spectrophotometric assay)
storage temp.	−20°C

产品描述

包装

1, 5 g in poly bottle

50, 100, 500 mg in poly bottle

Packaged by solid weight.

Application

β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).

As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

Biochem/physiol Actions

NADH is a coenzyme that functions as a regenerating electron donor in catabolic processes including glycolysis, β-oxidation and the citric acid cycle (Krebs cycle, TCA cycle). It participates in cell signaling events as well, for example as a substrate for the poly (ADP-ribose) polymerases (PARPs) during the DNA damage response. The NAD⁺/NADH dependent sirtuins play key roles in stress responses during events involving energy metabolism, with implications in cancer biology, diabetes and neurodegenerative disease.
As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.