FITC标记的磷酸化磷脂酰肌醇激酶3催化亚单位3抗体

FITC标记的磷酸化磷脂酰肌醇激酶3催化亚单位3抗体

价格: ¥2980

品牌:LMAI Bio

货号:LM-5581R-FITC

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供应商 :上海联迈生物工程有限公司

库存 :大量

靶点 :详见说明书

级别 :1

目录编号 :LM-5581R-FITC

克隆性 :多克隆

抗原来源 :Rabbit

保质期 :1年

抗体英文名 :Anti-phospho-PIK3C3(Ser164)/FITC

抗体名 :Anti-phospho-PIK3C3(Ser164)/FITC

标记物 :FITC标记

宿主 :Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,

适应物种 :Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,

免疫原 :详见说明书

亚型 :IGg

形态 :粉末、液体、冻干粉

应用范围 :IF=1:50-200

浓度 :1mg/ml

保存条件 :-20 °C

规格 :100ul

FITC标记的磷酸化磷脂酰肌醇激酶3催化亚单位3抗体
英文名称 Anti-phospho-PIK3C3(Ser164)/FITC
中文名称 FITC标记的磷酸化磷脂酰肌醇激酶3催化亚单位3抗体
别    名 PIK3C3(phospho S164); p-PIK3C3(phospho S164); p-PIK3C3(Ser164); PI 3 Kinase Class 3; Phosphatidylinositol 3 kinase catalytic subunit type 3; Phosphatidylinositol 3 kinase class 3; Phosphatidylinositol 3 kinase p100 subunit; Phosphoinositide 3 kinase class 3; PI3 kinase type 3; PI3K type 3; PIK3C3; PtdIns 3 kinase type 3; Vps 34; Vps34; hVps34; MGC61518.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 肿瘤  免疫学  信号转导  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human PIK3C3 around the phosphorylation site of Ser164
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
PI 3 Kinase Class 3 is a member of the PI3/PI4-kinase family. It is the catalytic subunit of the PI3K complex. It is involved in the transport of lysosomal enzyme precursors to lysosomes. It is ubiquitously expressed, with a highest expression in skeletal muscle.

Function:
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.

Subunit:
Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4. Forms a complex with BECN1, PIK3R4 and either UVRAG and KIAA0226/Rubicon, or with ATG14. In this complex, presence of UVRAG and ATG14 are mutually exclusive. Part of a complex composed of PIK3R4 and PIK3CB (By similarity). Interacts with RAB7A in the presence of PIK3R4.

Subcellular Location:
Midbody. Late endosome.

Tissue Specificity:
Ubiquitously expressed, with a highest expression in skeletal muscle.

Similarity:
Belongs to the PI3/PI4-kinase family.
Contains 1 C2 PI3K-type domain. 
Contains 1 PI3K/PI4K domain. 
Contains 1 PIK helical domain.

Database links:

Entrez Gene: 5289 Human

Entrez Gene: 225326 Mouse

Entrez Gene: 65052 Rat

Omim: 602609 Human

SwissProt: Q8NEB9 Human

SwissProt: Q6PF93 Mouse

SwissProt: O88763 Rat

Unigene: 464971 Human

Unigene: 194127 Mouse

Unigene: 30010 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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