FITC标记的细胞因子诱导凋亡抑制因子1

FITC标记的细胞因子诱导凋亡抑制因子1

价格: ¥2980

品牌:LMAI Bio

货号:LM-5764R-FITC

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供应商 :上海联迈生物工程有限公司

库存 :大量

靶点 :详见说明书

级别 :1

目录编号 :LM-5764R-FITC

克隆性 :多克隆

抗原来源 :Rabbit

保质期 :1年

抗体英文名 :Anti-CIAPIN1/FITC

抗体名 :Anti-CIAPIN1/FITC

标记物 :FITC标记

宿主 :Human, Mouse, Rat, Pig, Cow,

适应物种 :Human, Mouse, Rat, Pig, Cow,

免疫原 :详见说明书

亚型 :IGg

形态 :粉末、液体、冻干粉

应用范围 :IF=1:50-200

浓度 :1mg/ml

保存条件 :-20 °C

规格 :100ul

FITC标记的细胞因子诱导凋亡抑制因子1
英文名称 Anti-CIAPIN1/FITC
中文名称 FITC标记的细胞因子诱导凋亡抑制因子1
别    名 Anamorsin; CIAPIN 1; Cytokine induced apoptosis inhibitor 1; DRE2; CPIN1_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  细胞凋亡  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CIAPIN1 (101-200aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
CIAPIN1 (Cytokine induced apoptosis inhibitor 1) expression is dependent on growth factor stimulation. Overexpression confers resistance to apoptosis caused by IL3 deprivation. It may be required during hematopoiesis to mediate antiapoptotic effects of various cytokines. It also confers multidrug resistance in gastric cancer cells by upregulating the expression of MDR1 and MRP1. 

Function:
May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity). 

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ubiquitously expressed. Highly expressed in heart, liver and pancreas. 

Similarity:
Belongs to the anamorsin family. 

Database links:

Entrez Gene: 57019 Human

Entrez Gene: 109006 Mouse

Omim: 608943 Human

SwissProt: Q6FI81 Human

SwissProt: Q8WTY4 Mouse

Unigene: 4900 Human

Unigene: 27582 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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