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供应商 :上海联迈生物工程有限公司
库存 :大量
靶点 :详见说明书
级别 :1
目录编号 :LM-6570R-FITC
克隆性 :多克隆
抗原来源 :Rabbit
保质期 :1年
抗体英文名 :Anti-RING5/FITC
抗体名 :Anti-RING5/FITC
标记物 :FITC标记
宿主 :Human, Mouse, Rat, Dog, Pig, Horse,
适应物种 :Human, Mouse, Rat, Dog, Pig, Horse,
免疫原 :详见说明书
亚型 :IGg
形态 :粉末、液体、冻干粉
应用范围 :IF=1:50-200
浓度 :1mg/ml
保存条件 :-20 °C
规格 :100ul
FITC标记的环指蛋白5抗体(E3泛素蛋白连接酶RNF5)英文名称 | Anti-RING5/FITC |
中文名称 | FITC标记的环指蛋白5抗体(E3泛素蛋白连接酶RNF5) |
别 名 | E3 ubiquitin protein ligase RNF5; G16; HsRma1; NG2; OTTHUMP00000029107; Protein G16; Ring finger; protein 5; RING5; RMA1; RNF 5; RNF5_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 肿瘤细胞生物标志物 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Horse, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 20kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human RING5 (51-100aa) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions. Function: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD; the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the 'Lys-48'-linked polyubiquitination of TMEM173 at 'Lys-150' leading to its proteasomal degradation; the ubiquitination occurrs in mitochondria after viral transfection and regulates antiviral responses. Subunit: Interacts with PXN. Interacts with Salmonella typhimurium sopA. Interacts with JKAMP. Interacts with TMEM173; the interaction of endogenous proteins is dependent on viral infection. Subcellular Location: Membrane; Multi-pass membrane protein. Mitochondrion membrane. Endoplasmic reticulum membrane. Note=Predominantly located in the plasma membrane, with some localization occurring within cytoplasmic organelles. Tissue Specificity: Widely expressed. Similarity: Contains 1 RING-type zinc finger. Database links: Entrez Gene: 6048 Human Entrez Gene: 54197 Mouse Entrez Gene: 407784 Rat Omim: 602677 Human SwissProt: Q99942 Human SwissProt: O35445 Mouse SwissProt: Q5M807 Rat Unigene: 718462 Human Unigene: 274542 Mouse Unigene: 136937 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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