FITC标记的G2期/S期应答相关蛋白1抗体

FITC标记的G2期/S期应答相关蛋白1抗体

价格: ¥2980

品牌:LMAI Bio

货号:LM-7611R-FITC

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供应商 :上海联迈生物工程有限公司

库存 :大量

靶点 :详见说明书

级别 :1

目录编号 :LM-7611R-FITC

克隆性 :多克隆

抗原来源 :Rabbit

保质期 :1年

抗体英文名 :Anti-G2 and S phase expressed 1/FITC

抗体名 :Anti-G2 and S phase expressed 1/FITC

标记物 :FITC标记

宿主 :Human, Mouse, Rat, Dog, Cow, Horse, Sheep,

适应物种 :Human, Mouse, Rat, Dog, Cow, Horse, Sheep,

免疫原 :详见说明书

亚型 :IGg

形态 :粉末、液体、冻干粉

应用范围 :IF=1:50-200

浓度 :1mg/ml

保存条件 :-20 °C

规格 :100ul

FITC标记的G2期/S期应答相关蛋白1抗体
英文名称 Anti-G2 and S phase expressed 1/FITC
中文名称 FITC标记的G2期/S期应答相关蛋白1抗体
别    名 B99; B99 homolog; G 2 and S phase expressed 1; G two S phase expressed protein 1; GTSE 1; GTSE1_HUMAN .  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  染色质和核信号  信号转导  细胞凋亡  细胞周期蛋白  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Sheep, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 77kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GTSE1/G2 and S phase expressed 1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. 

Function:
May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression. 

Subcellular Location:
Cytoplasm, cytoskeleton. Note=Associated with microtubules. 

Post-translational modifications:
Phosphorylated in mitosis (By similarity).

Database links:

Entrez Gene: 51512 Human

Entrez Gene: 29870 Mouse

Entrez Gene: 300126 Rat

Omim: 607477 Human

SwissProt: Q9NYZ3 Human

SwissProt: Q8R080 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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