神经肌肉接头蛋白SNTA1抗体品牌

神经肌肉接头蛋白SNTA1抗体品牌

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品牌:上海博湖

货号:BH-K21831

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抗体名 :神经肌肉接头蛋白SNTA1抗体品牌

抗体英文名 :Anti-Syntrophin/SNTA1/Syntrophin Alpha1

靶点 :详见说明书

浓度 :1mg/1ml

应用范围 :WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

宿主 :详见说明书

供应商 :上海博湖

库存 :大量

级别 :详见说明书

目录编号 :详见说明书

抗原来源 :Rabbit

保质期 :详见说明书

适应物种 :详见说明书

标记物 :详见说明书

克隆性 :多克隆

保存条件 :Store at -20 °C

形态 :详见说明书

亚型 :IgG

免疫原 :KLH conjugated synthetic peptide derived from human Syntrophins/SNTA1

规格 :0.2ml/200μg

中文名称  神经肌肉接头蛋白SNTA1抗体品牌
英文名称  Anti-Syntrophin/SNTA1/Syntrophin Alpha1
     SNT1; SNT2; SNT3; SNTA1; SNTB1; SNTB2; Syntrophin alpha 1; Syntrophin beta 1; Syntrophin beta 2.
神经肌肉接头蛋白SNTA1抗体品牌是用于化学反应、分析化验、研究实验、教学实验、化学配方使用的纯净化学品,产品品质卓越,价格实惠,多种规格供应,售后完善。


     1mg/1ml
 0.2ml/200μg
抗体来源  Rabbit
克隆类型  polyclonal
交叉反应  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit
产品类型  一抗  
研究领域  细胞生物 免疫学 神经生物学
蛋白分子量  predicted molecular weight: 56kDa 
     Lyophilized or Liquid
 KLH conjugated synthetic peptide derived from human Syntrophins/SNTA1
     IgG
纯化方法   affinity purified by Protein A
 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide


神经肌肉接头蛋白SNTA1抗体品牌产品应用  WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复) 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
产品介绍 Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013].

Function : Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate (By similarity).
Subunit : Monomer and homodimer. Interacts with the other members of the syntrophin family SNTB1 and SNTB2; SGCG and SGCA of the dystrophin glycoprotein complex; NOS1; GRB2; the sodium channel proteins SCN4A and SCN5A; F-actin and calmodulin. Interacts with dystrophin protein DMD and related proteins DTNA and UTRN and with MAPK12, TGFA and GA.
Subcellular Location : Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell junction. Cytoplasm, cytoskeleton. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane and at neuromuscular junctions.
Tissue Specificity : High expression in skeletal muscle and heart. Low expression in brain, pancreas, liver, kidney and lung. Not detected in placenta.
Post-translational modifications : Phosphorylated by CaM-kinase II. Phosphorylation may inhibit the interaction with DMD.
DISEASE : Defects in SNTA1 are the cause of long QT syndrome type 12 (LQT12) [MIM:612955]. A heart disorder characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to excercise or emotional stress, and can present with a sentinel event of sudden cardiac death in infancy.
Similarity : Belongs to the syntrophin family.
Contains 1 PDZ (DHR) domain.
Contains 2 PH domains.
Contains 1 SU (syntrophin unique) domain.


神经肌肉接头蛋白SNTA1抗体品牌具有全、新、优、品、好四大特点:
全:公司提供上万种产品,涵盖了生物试剂,elisa试剂盒,标准品,培养基,原装耗材,抗体、培养基、ATCC细胞等,基本上各种科研所需产品在我司都能找到。
新:产品更新速度较快,基本上每周都有新产品出现。
优:产品质量好,投诉比较少。
好:我公司具有优质的技术团队,产品一旦售出,实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。
我们提供的标记服务,可根据您科研的需求,满足您的需要,质量保证,价格合理。
一、标记流程
委托标记服务,请下载并详细填写《委托标记申请单》,待我公司标记室技术人员研究、确认后答复,并办理委托标记事宜。
二、各种标记物制备的收费标准(RMB 
我们不但提供抗体和大分子蛋白的标记服务,还提供小分子多肽及小分子蛋白的各种标记服务,提供标记化合物的服务(此化合物必须适用于标记),价格另议。
一抗和二坑的区别:
第一抗体就是平常所说的抗体,即能和抗原特异性结合。
第二抗体是能和抗体结合的,即抗体的抗体。主要用于检测抗体的存在。
一抗是针对抗原的抗体,二抗是针对一抗的抗体。即抗体也可以充当抗原刺激机体产生抗体。也就是说,抗原进入机体刺激机体免疫系统产生免疫应答,由B细胞可以产生与相应抗原发生特异性结合的特殊蛋白质。
一抗二抗都是一种可以特异结合别的物质的基团,而且一抗可以至少结合两种其他基团(底物和二抗)。
一抗:可以特异结合底物,就是识别出我们想要检测的东西。一抗和底物结合与否用肉眼是看不出来的。
二抗:可以和一抗结合,并带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团),作用是检测一抗。 如果一抗自己带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团),则不需要二抗。但这样成本很高,因为一种一抗只识别一种底物。所以如今的设计一般是二抗带上可检测标记,再来检测一抗。而一抗识别底物。这样,当一抗结合到底物上,就可以通过二抗检测出来。 


Anti-p-VEGFR2/FITC 荧光素标记兔抗人、大、小鼠化血管内皮生长因子受体2抗体IgGMulti-class antibodies规格: 0.2ml
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IL1RAPL1 (Interleukin 1 receptor accessory protein-like 1) 白介素受体相关蛋白样1前体蛋白(抗原)Multi-class antibodies规格: 0.5mg

Anti-CD19 CD19抗体Multi-class antibodies规格: 0.1ml
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TBX2 英文名称: 新型抑癌基因抗体 0.2ml
TCP1 beta 英文名称: 分子伴侣复合体TCP-1β抗体 0.2ml
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Rabbit Anti-Guinea pig IgM/PE-Cy5.5 PE-Cy5.5标记的兔抗豚鼠IgM 0.1ml

FGFR5 英文名称: 成纤维细胞生长因子受体5抗体 0.1ml
内皮素-1抗体 Anti-ET-1 0.1ml
Anti-PERK/FITC 荧光素标记蛋白激酶R样内质网激酶抗体IgGMulti-class antibodies规格: 0.2ml
Rhesus antibody Rh phospho-Tau protein(Ser199) 化微管相关蛋白抗体 规格 0.1ml
Goat Anti-rat IgG/Gold 金标记羊抗大鼠IgG(10nm/15nm)Multi-class antibodies规格: 0.5ml
SW1116(人结肠腺癌细胞) 5×106cells/瓶×2

成纤维细胞cDNAHMF cDNA
MBL1 Others Rat 大鼠 MBL1 人细胞裂解液 (阳性对照)
HBL-100细胞,人细胞 兔肾细胞系,RK-13细胞 表皮角化细胞Many types of cells包装:5 × 105次方(1ml)
CL-0296MX-1(人癌细胞)5×106cells/瓶×2
HSaVEC Pellet 人隐静脉内皮细胞团块 > 1 mio.cells 间充质干细胞脂肪细胞分化生长添加物MADS
虹膜色素上皮细胞Many types of cells包装:5 × 105次方(1ml)

FCGR2B Others Cynomolgus 食蟹猴 CD32b / FCGR2B 人细胞裂解液 (阳性对照)
HBMEC 人脑微血管内皮细胞
中国仓鼠卵巢细胞K1(亚系克隆);CHO-K1
lovo, 人结肠癌细胞
人癌细胞;MDA-MB-157 大鼠小肠血管内皮细胞完全培养基 100mL
神经肌肉接头蛋白SNTA1抗体品牌SW1116(人结肠腺癌细胞) 5×106cells/瓶×2

成纤维细胞cDNAHMF cDNA
MBL1 Others Rat 大鼠 MBL1 人细胞裂解液 (阳性对照)
HBL-100细胞,人细胞 兔肾细胞系,RK-13细胞 表皮角化细胞Many types of cells包装:5 × 105次方(1ml)
CL-0296MX-1(人癌细胞)5×106cells/瓶×2
HSaVEC Pellet 人隐静脉内皮细胞团块 > 1 mio.cells 间充质干细胞脂肪细胞分化生长添加物MADS
 

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入驻年限:7年

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