FITC标记的血小板白细胞C激酶底物同源结构域M2抗体

FITC标记的血小板白细胞C激酶底物同源结构域M2抗体

价格: ¥2980

品牌:LMAI Bio

货号:LM-8063R-FITC

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供应商 :上海联迈生物工程有限公司

库存 :大量

靶点 :详见说明书

级别 :1

目录编号 :LM-8063R-FITC

克隆性 :多克隆

抗原来源 :Rabbit

保质期 :1年

抗体英文名 :Anti-PLEKHM2/FITC

抗体名 :Anti-PLEKHM2/FITC

标记物 :FITC标记

宿主 :Human, Mouse, Rat, Chicken, Cow, Horse,

适应物种 :Human, Mouse, Rat, Chicken, Cow, Horse,

免疫原 :详见说明书

亚型 :IGg

形态 :粉末、液体、冻干粉

应用范围 :IF=1:50-200

浓度 :1mg/ml

保存条件 :-20 °C

规格 :100ul

FITC标记的血小板白细胞C激酶底物同源结构域M2抗体
英文名称 Anti-PLEKHM2/FITC
中文名称 FITC标记的血小板白细胞C激酶底物同源结构域M2抗体
别    名 PH domain containing family M member 2; Pleckstrin homology domain containing family M (with RUN domain) member 2; Pleckstrin homology domain containing family M member 2; PLEKHM 2; RP11 169K16.1; Salmonella induced filaments A and kinesin interacting protein; SifA (Salmonella induced filaments A) and kinesin interacting protein; SifA and kinesin interacting protein; SKIP; KIAA0842; Novel RUN and PH domain containing protein; PKHM2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  细菌及病毒  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Cow, Horse, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 113kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PLEKHM2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.

Function:
May play a role in the regulation of conventional kinesin activity. Required for maintenance of the Golgi apparatus organization. May play a role in membrane tubulation.

Subunit:
Interacts with KIF5B. Interacts with the S.typhimurium sifA protein; required for S.typhimurium infection.

Subcellular Location:
Cytoplasm.

Similarity:
Contains 1 PH domain. 
Contains 1 RUN domain.

Database links:
UniProtKB/Swiss-Prot: Q8IWE5.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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