FITC标记的FBXL15蛋白抗体

供应商 ：上海联迈生物工程有限公司

库存 ：大量

靶点 ：详见说明书

级别 ：1

目录编号 ：LM-8475R-FITC

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：1年

抗体英文名 ：Anti-FBXL15/FITC

抗体名 ：Anti-FBXL15/FITC

标记物 ：FITC标记

宿主 ：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,

适应物种 ：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,

免疫原 ：详见说明书

亚型 ：IGg

形态 ：粉末、液体、冻干粉

应用范围 ：IF=1:50-200

浓度 ：1mg/ml

保存条件 ：-20 °C

规格 ：100ul

FITC标记的FBXL15蛋白抗体

英文名称	Anti-FBXL15/FITC
中文名称	FITC标记的FBXL15蛋白抗体
别    名	F box and leucine rich repeat protein 15; F box only protein 37; F box/LRR repeat protein 15; Fbl15; FBXO37; FLJ16137; JET; OTTHUMP00000020367; OTTHUMP00000059115; OTTHUMP00000059124; OTTHUMP00000059125; Pleckstrin and Sec7 domain protein; PSD; MGC11279; FXL15_HUMAN.
规格价格	100ul/2980元 购买        大包装/询价
说 明 书	100ul
研究领域	细胞生物  免疫学
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
产品应用	IF=1:50-200   not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	33kDa
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human FBXL15
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍	background: FBXL15 probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune responses, signaling cascades and developmental events) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors. FBL15 (F-box and leucine-rich repeat protein 15), also known as FBXL15, FBXO37, PSD or JET, is a 296 amino acid protein that contains one F-box domain and functions as a component of the SCF complex, possibly playing a role in the ubiquitination and subsequent degradation of target proteins. Function: Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.  Subunit: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXL15) composed of CUL1, SKP1, RBX1 and FBXL15. Subcellular Location: Cytoplasm. Similarity: Belongs to the FBXL15 family.  Contains 1 F-box domain.  Contains 5 LRR (leucine-rich) repeats.  Database links: UniProtKB/Swiss-Prot: Q9H469.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.