FITC标记的热休克蛋白70相互作用蛋白抗体

供应商 ：上海联迈生物工程有限公司

库存 ：大量

靶点 ：详见说明书

级别 ：1

目录编号 ：LM-11271R-FITC

克隆性 ：多克隆

抗原来源 ：Rabbit

保质期 ：1年

抗体英文名 ：Anti-HSPABP/HIP/HSC70 Interacting Protein HIP/FITC

抗体名 ：Anti-HSPABP/HIP/HSC70 Interacting Protein HIP/FITC

标记物 ：FITC标记

宿主 ：Human

适应物种 ：Human

免疫原 ：详见说明书

亚型 ：IGg

形态 ：粉末、液体、冻干粉

应用范围 ：ICC=1:50-200 IF=1:50-200

浓度 ：1mg/ml

保存条件 ：-20 °C

规格 ：100ul

FITC标记的热休克蛋白70相互作用蛋白抗体

英文名称	Anti-HSPABP/HIP/HSC70 Interacting Protein HIP/FITC
中文名称	FITC标记的热休克蛋白70相互作用蛋白抗体
别    名	AAG 2; AAG2; Aging associated protein 2; F10A1_HUMAN; FAM10A1; FAM10A4; FLJ27260; Heat shock 70kD protein binding protein; HIP; HOP; Hsc70 interacting protein; Hsc70-interacting protein; Hsp70 interacting protein; HSPABP 1; HSPABP; HSPABP1; MGC129952; OTTHUMP00000028873; P48 antibody PRO0786; Progesterone receptor associated p48 protein; Progesterone receptor-associated p48 protein; Protein FAM10A1; Putative tumor suppressor ST13; Renal carcinoma antigen NY REN 33; Renal carcinoma antigen NY-REN-33; SNC 6; SNC6; ST 13; ST13; Suppression of tumorigenicity 13; Suppression of tumorigenicity 13 (colon carcinoma); Suppression of tumorigenicity 13 protein; Suppression of tumorigenicity protein 13.
规格价格	100ul/2980元 购买        大包装/询价
说 明 书	100ul
研究领域	细胞生物  信号转导  细胞凋亡
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human,
产品应用	ICC=1:50-200 IF=1:50-200   not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	41kDa
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human HSPABP
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍	background: Hip (HSP70-interacting protein), also known as ST13 (suppression of tumorigenicity protein 13), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1,2). The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3). By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8). Function: One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins. Subunit: Homotetramer. Interacts with HSC70 as well as DNAJ homologs and HSP90 (By similarity). Interacts (via the C-terminus 303- 319 AA) with GRK5. Subcellular Location: Cytoplasm. Similarity: Belongs to the FAM10 family.  Contains 1 STI1 domain.  Contains 3 TPR repeats. Database links: Entrez Gene: 281506 Cow Entrez Gene: 6767 Human Entrez Gene: 70356 Mouse Entrez Gene: 81800 Rat Omim: 606796 Human SwissProt: P50502 Human SwissProt: Q99L47 Mouse SwissProt: P50503 Rat Unigene: 712713 Human Unigene: 180337 Mouse Unigene: 119613 Rat Unigene: 8796 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications