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英文名 :Recombinant Human Beta Defensin -2
库存 :大量
规格 :20ug
重组人β防御素2,BD-2,DEFB2Recombinant Human BD-2
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Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Human BD-2 is a 4.3 kDa protein containing 41 amino acid residues.
Source: E.coli
Synonyms: DEFB2, DEFB4A, Beta-Defensin 2, Skin-antimicrobial peptide 1, SAP1
AA Sequence: GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by its ability to chemoattract immature human dendritic cells using a concentration of 10.0-100.0 ng/ml.
Calculated Molecular Weight: 4.3 kDa
Accession Number: O15263
Gene ID: 1673
上海研卉生物科技有限公司
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入驻年限:10年