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库存 :525
英文名 :Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9
保质期 :6个月
供应商 :北京百奥莱博科技有限公司
保存条件 :收到货后请置于-20℃
特别提示:包括重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人PCSK9(前蛋白转化酶枯草杆菌蛋白酶kexin-9)(C端His标签)
英文名称:Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9
产品规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gln31-Gln152&Ser153-Gln692在C端含有His标签。
PCSK9质量控制:>95%(还原性SDS-PAGE)
PCSK9制剂:液体
PCSK9保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于PCSK9:
Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.
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入驻年限:9年