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英文名 :≥98% (HPLC)
库存 :50
CAS号 :905973-89-9
规格 :5mg/25mg/100mg
一种有效的ATM/ATR选择性抑制剂。CGK733 was originially published as a cell permeable compound that selectively inhibits the kinase activity of ATM and ATR at an IC50 ~ 200 nM without significant effect against other PIKK family members DNA-PK, mTOR and PI 3-kinase (PI3K) or kinases that are known to phosphorylate p53 (ERK, Cytokeratin 1(CAK), Cdk2, JNK, PKC, cyclin H(CAK), Chk1, PKR, and p38). The claims of this product we retracted and the effect of the ATM/ATR Kinase Inhibitor (CGK733) have not been fully investigated.北京普西唐生物科技有限公司
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