SENP7泛素特异性蛋白酶SENP7抗体

SENP7泛素特异性蛋白酶SENP7抗体

价格: ¥1380 - 2200

品牌:LMAI Bio

货号:LM-8698R

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供应商 :上海联迈生物工程有限公司

库存 :大量

目录编号 :LM-8698R

克隆性 :多克隆

抗原来源 :Rabbit

保质期 :1年

抗体英文名 :SENP7

抗体名 :泛素特异性蛋白酶SENP7抗体

宿主 :Rabbit

适应物种 :Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

免疫原 :KLH conjugated synthetic peptide derived from human SENP7:931-1050/1050

亚型 :IgG

形态 :Lyophilized or Liquid

应用范围 :ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)

浓度 :1mg/ml

保存条件 :Store at -20 °C

规格 :100ul  200ul

SENP7泛素特异性蛋白酶SENP7抗体
英文名称 SENP7
中文名称 泛素特异性蛋白酶SENP7抗体
别    名 KIAA1707; Senp7; SENP7_HUMAN; Sentrin specific protease; Sentrin-specific protease 7; Sentrin/SUMO-specific protease SENP7; SSP2; SUMO 1 specific protease 2; SUMO specific protease; SUMO-1-specific protease 2; SUMO1/sentrin specific peptidase 7; SUSP2.  
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 119kDa
细胞定位 细胞核 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SENP7:931-1050/1050 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]

Function:
Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms.

Similarity:
Belongs to the peptidase C48 family.

SWISS:
Q9BQF6

Gene ID:
57337

Database links:

Entrez Gene: 57337 Human

Entrez Gene: 66315 Mouse

Omim: 612846 Human

SwissProt: Q9BQF6 Human

SwissProt: Q8BUH8 Mouse

Unigene: 529551 Human

Unigene: 255784 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
 
产品图片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SENP7) Polyclonal Antibody, Unconjugated (bs-8698R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.

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