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USP7/USP47 inhibitor

CAS No. : 1247825-37-1

MCE 国际站：USP7/USP47 inhibitor

产品活性：USP7/USP47 inhibitor 是一种选择性的泛素蛋白特异性蛋白酶 7/47 (USP7/USP47) 抑制剂，EC₅₀ 值分别为 0.42 μM 和 1.0 μM。

研究领域：Cell Cycle/DNA Damage

作用靶点：Deubiquitinase

In Vitro: USP7/USP47 inhibitor (compound 14) is a selective inhibitor of USP7/USP47 with EC₅₀s of 0.42 μM and 1 μM, respectively. USP7/USP47 inhibitor does not inhibit caspase 3, calpain 1, 20S proteasome, and a panel of representative USPs (USP2, USP5, USP8, USP21, and USP28; EC₅₀ > 31.6 μM). USP7/USP47 inhibitor inhibits the growth of HCT-116 cells with an EC₅₀ of 7.6 μM.

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